Sentence examples for an established importance from inspiring English sources

We discuss predicted functions for the gene products of MLH1, PMS2 and EPHB4, all of which have an established importance for colorectal cancer [ 67, 68].

Although reactive oxygen species (ROS) have an established importance in the pathogenesis of cardiovascular diseases (Dhalla et al. 2000), their specific impact on autonomous nervous system activity and its reaction to inhalants remains to be established.

In this study, we included all breast cancer cases diagnosed within a population of over 3.6 million, and estimated the relative risk of death in relation to surgical workload after adjusting for a range of patient factors of established importance.

Relative size established importance: the ruler dwarfed the generally high official, while the tomb owner dwarfed his wife and, still more so, his children.

Besides their established importance in the NMD process per se, NMD components have also been reported to play roles in other cellular pathways.

Based on the well established importance of fungal laccases and related enzymes in lignin degradation [ 48, 49], phenoloxidases/laccases are also relevant to industrial lignocellulose pretreatment.

Second, LMICs with substantial pharmaceutical markets, such as India, Brazil and Thailand, can provide leadership and establish importance precedence by asserting the flexibilities available under TRIPS to protect public health.

The Gram-positive soil bacterium, Bacillus subtilis, is an established model organism of industrial importance.

The procedure has been an established one ever since the importance of Ilizarov's research was recognized.

In the past 8 years, external quality controls emphasized the importance of an established knowledge of the genes being tested by the diagnostic personnel to guarantee the reliable conclusion of genetic testing (5).

The history of controversy surrounding autism makes this area suitable for this pilot project and is certainly illustrative of the importance of an established methodology for determining credible knowledge in the field of CYMH.