Sentence examples for an established effect of from inspiring English sources

Hence, heparin-induced changes of the activation current at fertilization [25], [48] may have caused the increased frequency of polyspermy, which is an established effect of heparin, as a result of the failed 'electrical block.' The fast blockade of supernumerary sperm entry by this mechanism of fertilization membrane depolarization has been also reported in starfish eggs [5].

Nevertheless, screening results in an established effect, i.e. the increased frequency of smaller tumour size at the time of diagnosis that has been observed in every trial that has been conducted.

In accordance with the established effect of SHP2 on STAT3, knockdown of SHP2 siRNA resulted in an increase in phospho-STAT3 without a significant increase in total STAT3 levels.

We also investigated the association between type A behavior and CAD-related mortality in those already diagnosed with CAD and whether the established effect of depressive symptomatology on CAD incidence interacted with or explained any effect of type A behavior.

Together with the established effect of ASA in colon cancer prevention, the findings presented here might thus be able to contribute to interest in a careful reevaluation of ASA therapy in patients with UC with its high risk of colon cancer development, possibly in combination with DHA supplementation.

Since enhancement of platelet-dependent thrombin generation is an established outcome of P2Y12 signaling [20], effects of P2Y12 antagonism on thrombin generation were investigated in mouse and human PRP.

In our case control study of endometrial cancer risk after tamoxifen in the same population (Swerdlow and Jones, 2005), for which there is a well-established effect of tamoxifen on risk, cancer risks in users with an unknown dose and duration of treatment were similar to those in patients with known intermediate values of these variables.

A well-established effect of animated agents in educational and other contexts is their potential to motivate and engage.

This effect is a well-established effect of caloric restriction, which is known to cause decreases in circulating glucose levels and increased insulin sensitivity.

Our simulations reproduce a well-established effect of population growth (Slatkin and Hudson 1991; Wakeley 2008; Coventry et al. 2010; Keinan and Clark 2012; Nelson et al. 2012; Tennessen et al. 2012) by showing an increase in the proportion of singletons (sites with DAC = 1).

This is a well-established effect of this drug, and is commonly used; we simply included a trace to make sure the drug was effective (this control trace is not normally included in publications and could be removed to save space).