The phrase "an essential target" is correct and usable in written English.
It can be used when referring to a goal or objective that is crucial or necessary in a particular context, such as business, project management, or strategic planning.
Example: "In our marketing strategy, increasing brand awareness is an essential target that we must achieve this quarter."
Alternatives: "a critical goal" or "a key objective."
Viral entry is an essential target step for antiviral development, but FDA-approved HCV entry inhibitor remains exclusive.
HCV entry is an essential target step for antiviral development, but FDA-approved HCV entry inhibitor remains exclusive.
Cooling of buildings is an essential target for engineers and builders in the hot arid climate of Egypt.
As the exopeptidase over-expressed in the cell surface of endothelial cells, aminopeptidase N (APN/CD13) is an essential target for tumor angiogenesis and metastasis.
T. brucei is the parasite which causes African sleeping sickness, a neglected tropical disease that affects thousands each year, and TbrPDEB1 has been shown to be an essential target of therapeutic relevance.
It's true that women have become an essential target segment for the wine industry when it comes to marketing -- 53percentt of wine drinkers in the U.S. are women, according to the Wine Market Council, and last year, women matched men as "core drinkers," those who drink wine at least once a week.
Such presequences are easily recognized due to an essential targeting motif with a characteristic signature at the signal peptide cleavage site [16], [17].
In addition to AdoMetDC, SpdS may provide an essential targeting point in T. cruzi polyamine metabolism.
These results suggest that protein-O-glycosylation is an essential process in C. neoformans, and that either Pmt1 and Pmt4 both interact with Pmt2 to provide the cell with optimal protein-O-mannosylation activity or that Pmt1 and Pmt4 have a common essential target independent of Pmt2.
We believe that the reason for this variation is that an essential molecular target or targets is present in the T. brucei parasite which can be modulated by compounds with a similar pharmacophore to that required for TbGSK3 inhibition.
A "perfect" predicted essential target would be one without (or with non-essential) potential cross-reactivity targets in human and E. coli (as a proxy for gram-negative and gut flora in general), with essential homologs in B. subtilis and up-regulated in vivo.
