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Both cell types inducibly express RANKL, which is an essential stimulating signal for osteoclastogenesis and is also involved in the activation of mature osteoclasts [ 3, 17].
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In addition to co-stimulatory molecules CD80 and CD86, more cytokines were produced by RBcs-exposed DCs, such as IL-12, an essential cytokine stimulating Th1 responses.
Although the clinical benefit of dynamisation in fresh tibial fractures is debated, the technique is generally accepted as an essential method of stimulating fracture healing in delayed and nonunions [52, 53, 54, 55, 56].
Interferon-γ (IFNγ) plays an essential role in stimulating cells to eliminate intracellular pathogens [57].
Parents, friends and family members play an essential part in stimulating adolescents' educational growth, as learning extends beyond the classroom.
These data indicate that Sirt1 plays an essential role in stimulating AMPK, and improves mitochondrial function both in vitro and in vivo[ 89].
Elongation factor P (EF-P) is an essential protein that stimulates the formation of the first peptide bond in protein synthesis.
Mechanical tension, produced by force generation and stretch, is an essential factor to stimulate signaling pathways involved in muscle growth, and the combination of these stimuli appears to have a marked additive effect [ 9, 19, 20].
Often, in fact, the establishment of processing facilities is itself an essential first step towards stimulating both consumer demand for the processed product and an adequate supply of the raw material.
Zinc (Zn) is an essential trace element which stimulates the activity of many enzymes.
In this essay, we speculate that these changes in gene expression play an essential role during regeneration by stimulating the anabolic pathways required for the reconstruction of a new appendage.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com