Sentence examples for an essential step in the pathogenesis from inspiring English sources

The accumulation of Plasmodium falciparum parasitized erythrocytes (PEs) within the placenta is believed to be an essential step in the pathogenesis of PM [3].

The Haemophilus influenzae HMW1 protein is a high-molecular weight non-pilus adhesin that mediates attachment to human epithelial cells, an essential step in the pathogenesis of H. influenzae disease [1] [3].

Aspiration of oropharyngeal secretions and gastric contents containing bacteria is considered an essential step in the pathogenesis of VAP.

Accumulating evidence has demonstrated that ER stress-induced cell death is an essential step in the pathogenesis of a wide variety of cardiovascular diseases such as ischemia reperfusion heart diseases, atherosclerosis, myocardial infarction, hypertension and heart failure.

This fact drove us to investigate the possible role HDAC may have in the pathogenesis of OA, for chondrocyte hypertrophy is an essential step in the process of endochondral ossification [ 9], which has an important role in both cartilage degradation and osteophytes formation.

This is an essential step in the design process.

Mutations in the MET oncogene are an essential step into the pathogenesis of hereditary pRCC forms, but they can be found only in a small rate of sporadic cases.

Angiogenesis represents a crucial step in the pathogenesis of endometriosis, because endometriotic lesions require neovascularization.

Polymerization into amyloid fibrils is a crucial step in the pathogenesis of neurodegenerative syndromes.

Activation of hepatic stellate cells (HSCs) is a crucial step in the pathogenesis of hepatic fibrosis.

The subtraction procedure is an essential step in our method.