Sentence examples for an essential role in the pathogenesis from inspiring English sources

LDL is the major cholesterol-carrying lipoprotein of human plasma and plays an essential role in the pathogenesis of atherosclerosis34.

The balance between proteases and antiproteases plays an essential role in the pathogenesis of emphysema.

Rather, intricate interactions between tumor cells and their stromal microenvironment play an essential role in the pathogenesis of metastasis.

Impaired GABAergic inhibitory synaptic transmission plays an essential role in the pathogenesis of selective neuronal cell death following transient global ischemia.

Accumulating evidence suggests that inflammation plays an essential role in the pathogenesis of atherosclerosis and that circulating inflammatory markers predict future cardiovascular events.

Various studies indicate that NO plays also an essential role in the pathogenesis of migraine [22, 23].

It is believed that IR, oxidative stress, and inflammatory cascade play an essential role in the disease pathogenesis and progression.

Autophagy plays an essential role in the clearance of aggregate-prone proteins and damaged mitochondria, and dysfunctional autophagy has been implicated in the pathogenesis of PD (37).

Human genetics studies have greatly informed us about AD pathogenesis and strongly suggest that cerebral Aβ accumulation has an essential role in the etiology of AD [ 2].

Here, we show that metabolites of neurons play essential role in the pathogenesis of Alzheimer's disease (AD).

These findings support the notion that inhibiting antithrombin activity plays an essential role in RA pathogenesis.