Sentence examples for an essential player that from inspiring English sources

Indeed, our findings establish FAK as an essential player that facilitates the oncogenic conversion of TGF-β in developing and progressing mammary tumors, leading to their acquisition of invasive and metastatic phenotypes in response to TGF-β.

Notably, platelets express CD40L, an essential player in host defense against infection that mediates interactions between platelets, antigen-presenting cells, and lymphocytes [15].

The mitochondrial enzyme DLST is an essential player in the citric acid cycle that warrants proper adenosine-tri-phosphate (ATP) production.

And despite the widespread GOP losses, the group has argued that it was an essential player precisely because the DSCC was so strong at fundraising.

It was found that when MDM2 levels in the knocked-down cells were reduced, PIR remained cytoplasmic even following treatment with proteasome inhibitors, indicating that MDM2 is an essential player in the nuclear localization of NLS-deficient PIR.

We have found that the native Nde1 protein in the developing mouse tissue is very insoluble and exists at a relatively low level, but genetic studies have shown that Nde1/NDE1 is an essential player for various pivotal aspects of the neural progenitor biology.

In lymphomas, it is increasingly apparent that the microenvironment is an essential player not only for lymphoma pathogenesis but also for disease progression and therapy resistance.

In that case, the moths are an essential player, as they act like fertilizer when they die, the algae consume the nutrients in their remains.

Kerry told a press conference that the new Administration considered Syria "an essential player in bringing peace and stability to the region".

Our results show that Dnmt1 haploinsufficiency leads to an early onset of reduction in BMD in both male and female mice, suggesting that DNA methylation may function as an essential player in bone biology.

Moreover, we demonstrate that the AP-2α regulated gene Axl is an essential player in GN-11 neuron migration.