Sentence examples for an essential player of from inspiring English sources

Similarly, we detected nucleocytoplasmic shuttling of RAN, an essential player of the RAN-dependent nucleocytopasmic transport [ 30, 31].

The PQC consists of molecular chaperones and degradation systems and is an essential player of the proteotoxic stress response.

The human 18q21.1-q21.2 region, constantly disrupted in human CRC [ 15, 16], encodes the bona fide CRC gene SMAD4, which is an essential player of the transforming growth factor-β (TGF-β) signaling pathway.

By taking advantage of a medaka model that recapitulates the MLS phenotype we demonstrate that downregulation of hccs, an essential player of the mitochondrial respiratory chain (MRC), causes increased cell death via an apoptosome-independent caspase-9 activation in brain and eyes.

We have found that the native Nde1 protein in the developing mouse tissue is very insoluble and exists at a relatively low level, but genetic studies have shown that Nde1/NDE1 is an essential player for various pivotal aspects of the neural progenitor biology.

While traditionally viewed as relatively simple and short-lived effector cells, recent findings on novel neutrophil functions have resulted in a shifting paradigm wherein neutrophils are implicated as an essential player in modulation of multiple early immune responses13.

"The media are an essential player in all of this," Bonn says.

One of the starch debranching enzymes, isoamylase (ISAI), is an essential player in the formation of crystalline amylopectin [ 18].

That caveat also includes Al Nusra Front, the Al Qaeda affiliate that has been an essential player in the ranks of the Syrian armed opposition since early 2012.

Taken together, p68 is shown to be an essential player in the regulation of H-Ras expression as well as in a vital transduction signal pathway tied to cell proliferation and many cancer processes.

A possible candidate for the DFNA47 locus is the transcription factor Nfib, an essential player in the maturation of lungs and brain development [ 30].