Sentence examples for an essential host from inspiring English sources

Although granulomas may be an essential host response against persistent antigens, they are also associated with immunopathology.

Curiously, the adaptation of HBV to utilize HNF4α, an essential host gene product, guarantees constitutive replication of its genome as long as the host is viable.

This approach is expected to establish a significant barrier against spontaneous viral escape from inhibition, since individual viral mutations are less likely to compensate for the loss of an essential host cofactor than to prevent high-affinity binding of a conventional, pathogen-directed antiviral.

Taken together, we identify SK2 as an essential host factor during CHIKV infection.

Human La protein is known to be an essential host factor for the translation and replication of HCV RNA [ 32].

Nlrp1b activation by LT represents an essential host defense mechanism in the control of B. anthracis infection.

Importantly, we established an essential host-parasite interdependence that dictates the biosynthetic activity of the parasite.

Type I interferons (IFNs) represent an initial and essential host defense response against viruses.

A total of 1,501 essential host factors (EHFs) are listed in Additional file 7. The rational of this integrative approach relies on the potential existence of pan-viral host co-factors [ 6], as a result of shared viral lifecycle steps - including virus integration, replication and egress from the cell - and similar cellular defence mechanisms subverted by viruses.

The innate immune system provides essential host defense against a wide variety of microbial pathogens.

Indispensable to chlamydial growth and development is the establishment of an intracellular niche that avoids immune response but allows the acquisition of essential host nutrients [5].