Trihydroxynaphthalene reductase (3HNR) is an essential enzyme in the biosynthesis of fungal melanin and it represents an emerging target for the development of new fungicides and antimicotics.
The human immunodeficiency virus type 1 (HIV-1) integrase (IN) is an essential enzyme in the life cycle of the virus and is an attractive target for the development of new drugs useful in acquired immunodeficiency syndrome multidrug therapy.
LpxC is an essential enzyme in the lipid A biosynthetic pathway in gram-negative bacteria.
Dihydrodipicolinate synthase (DHDPS) is an essential enzyme in (S -lysine bioS -lysine and an important antibiosynthesist.
Phosphomannomutase (PMM) is an essential enzyme in eukaryotes.
Here we describe the development of a robust assay for apurinic/apyrimidinic (AP) endonuclease 1 (anessential), an enzymeinvolvedme involved in the repair of oxidative DNA damage.
Myeloperoxidase is an essential enzyme for the production of reactive oxygen species (ROS), which are involved in many biological processes contributing to the development and progression of heart failure [ 5].
Vitamin C is an essential enzyme cofactor in reactions catalyzed by several metal-dependent oxygenases[20].
HIV-1 integrase, which catalyzes the integration of the viral genome into the cellular chromosome, is an essential enzyme for retroviral replication, and represents an attractive and validated target in the development of therapeutics against AIDS.
HIV-1 integrase (IN) is an essential enzyme for effective viral replication and is a validated target for the development of antiretroviral drugs.
