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Numerous molecular studies over the years have presented p53 as an essential controller of cellular and genome integrity [1].
STIM1 has been identified as an essential controller of SOCE [5], [6], but reports on the role of STIM2 in the SOCE process have been inconsistent.
However, Rac is also an essential controller of cytoskeletal re-arrangements in many cells [36], and its perturbation leads to large-scale anatomical defects during Purkinje neuron maturation [37].
Interestingly, the nutrient-sensing TOR pathway that is activated by insulin, growth factors and nutrients is an essential controller of cell growth.
Sirolimus is an inhibitor of mammalian target of rapamycin (mTOR), a kinase enzyme which is an essential controller of cellular and organism growth that integrates nutrient and hormonal signals, and regulates multiple cellular processes.
In conclusion, the Rac-FRET mouse strain has enabled us to monitor the intricate and dynamic regulation of the small G protein Rac, an essential controller of distinct biological responses depending on timing, location, and signaling context.
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Remarkably, TOR is structurally and functionally conserved from yeast to human (including worms, flies, plants and mice) as an essential, central controller of cell growth [ 1].
It is thus the essential controller of HOG pathway activity, and variations in its concentration could compromise fitness.
As friction models are needed to diagnose abnormal valve operation or to compensate such undesirable effects, process models play an essential role in controller design.
Airport officials said the staging of the control tower was a major step forward because the new location placed controls about 80 feet above the runway, or only 20 feet lower than they were at the regular tower, giving controllers an essential view of the runways and decreasing the time between takeoffs or landings imposed after the quake.
Parametric design of satellite tracking controller is an essential for almost modern satellites.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com