Sentence examples for an essential anchor from inspiring English sources

"Even with these potential design alterations," Mr. Sartor said, "the hub will retain its signature 'winged' design, provide enhanced transportation services and substantial public space for commuters, residents and visitors alike, and serve as an essential anchor to the broader redevelopment of the World Trade Center site and Lower Manhattan".

The Polish ecclesiastical province effectively served as an essential anchor and an institution to fall back on for the Piast state, helping it to survive in the troubled centuries ahead.

MyD88 is an essential anchor protein that integrates and transduces intracellular signals generated by the Toll-like or IL-1 receptor (TLR or IL-1R) superfamily [14], [15].

LAMTOR1 also serves as an essential anchor for the p14-MP1 MEK ERK pathway in late endosomes/lysosomes.

Lipid A is an essential hydrophobic anchor of LPS and the first committed step in lipid A biosynthesis is catalyzed by a unique zinc dependent metalloamidase, UDP-3-O- R-3-hydroxymyristoyl -N-acetylglucosamine UDP-3-O- R-3-hydroxymyristoyl -N-acetylglucosamine

The experience has given the time and fuel to think about the essential anchor that work provides to so many people — not just in terms of income, but also in terms of self, friendship and purpose — and yet how easily this anchor can be cut away from us, its moorings, setting us adrift.

Rather than serving as just one more recreational option, children's museums are recasting themselves as essential anchors in their communities — "the hub or the center," Mr. Ackerman said.

Desmosomes are essential anchoring junctions that enforce adhesion through contacts to the intermediate filament cytoskeleton, forming a robust network among adjacent cells that confers strength and resiliency to the epidermis (reviewed in 21, 22).

Therefore, it has not been clear to what extent the loss of BicD function alters actual transport of the cargo in question, as opposed to what extent it plays an essential role in anchoring the cargo once it is appropriately delivered.

p21Ras is among the most prominent of these enzymes and prenylation of p21Ras with a farnesyl moiety by the enzyme farnesyl transferase is an essential step in anchoring p21Ras to the plasma membrane in readiness for GTP loading and signalling via the MAPK pathway.

Tetherin constitutively resides in cholesterol-rich microdomains by virtue of its GPI anchor (an essential attribute for signaling) (Kupzig et al., 2003).