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In a study by van den Bemt, an error frequency of 56% fell to 34% when they excluded timing errors.
An error frequency of up to 33% has been reported for differences in ≥ one fibrosis stage and cirrhosis may be missed in 10 30% of blind biopsies [ 40].
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They do so with extremely high fidelity, exhibiting an error frequency in the range of 1 in 10 10 mistakes per incorporation event depending on the presence or absence of an intrinsic exonuclease activity.
The reported Tgo DNA polymerase from the Roche product manual has an overall error frequency of ~0.2% in nucleotide misincorporation during PCR amplification, very close to what we found in our study.
Our findings indicate a considerable error frequency of ~1-6~1-6%
We observed a sequencing error frequency of ~0.5-1% on the Illumina GAIIx.
The polymerase error frequency of a specific type of error (e.g., indel within the repeat or indel at a monitor locus) was calculated from the proportion of the specific mutants (among the total sequenced) multiplied by polymerase error frequency for each template.
The prediction error of Dolphin Imaging VTO was analyzed by tabulating the error frequency of subjects within the range of acceptable error in both the X-axis (Table 2) and Y-axis (Table 3).
The basal error frequency of the eukaryotic ribosome is 4 × 10– to 10–.
Accordingly, it is possible that (a) mutations may be modulated by other viral polypeptides cooperating with Pol, and (b) the localized secondary structure of the viral genome may partially account for the apparently enhanced error frequency of HSV-2.
In the simulated C. intestinalis data set (Methods), a single stretched exponential distribution provided a good fit to the frequency of genotype calling errors as a function of the call confidence score for scores up to 6, or down to error frequency of approximately 1%.
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