Moreover, the recovery in neutrophil chemotaxis was associated with an enhancement in CXCR2 expression on the neutrophil surface and a reduction in GRK2 induction.
Interestingly, MMTV-Wnt1-driven tumors show an enhancement in ILK expression and a requirement for ILK activity for cyclin D1 upregulation [ 20].
In human MKs grown in the presence of either aspirin or WY14643, MRP4 and PPARα-mRNA were higher than in control cultures and derived platelets showed an enhancement in MRP4 protein expression.
Using pure astrocyte cultures, as well as, mixed cortical cell cultures containing both neurons and astrocytes, we found that neither an enhancement in system xc− expression nor activity underlies the excitotoxic effects of aglycemia.
The Gfra1 transcript had previously been shown to be upregulated in SSCs following rapamycin exposure, and it exhibited a 3.13-fold enhancement in expression here (Table 1)[ 12].
This was not so for fibronectin, where we observed an enhancement of expression in the SPARC−/− wounds in vivo, in apparent contradiction to the in vitro failure to upregulate its expression in response to TGF-β2.
Moreover, we observed the greatest enhancement in expression of the neuronal marker β-tubulin III within the softest hydrogels, which had an elastic modulus comparable to that of brain tissues.
Vascular endothelial growth factor and Flt-1 gene expression were increased significantly in the fetal membrane and decidua samples that were obtained from the noninflamed tissues from group 2B (P <.005) yet showed further enhancement in expression in the inflamed tissues.
The UEP1 promoter in ray florets was reported to confer over 50-fold enhancement in expression as compared to CaMV 35S-based promoters.
The enhancement in expression levels and defense response revealed by RNA-Seq results in the resistant genotype was confirmed by the real-time RT-PCR, in line with an enhanced Fusarium responsiveness at 72 hpi in this genotype.
Previous studies observed that morphine induces lymphocyte apoptosis through mechanisms associated with a decrease in anti-apoptotic protein Bcl-2 expression and an enhancement in that of pro-apoptotic protein Bax [43], [44].
