Sentence examples for an enhanced selection of from inspiring English sources
In addition, it appears to be of increasing importance to study mechanisms in the cell environment (the stem cell niche and in the circulatory environment) that may lead to an enhanced selection of mutant stem and progenitor cells during ageing.
Nevertheless, we show here for the first time to our knowledge that expression of an endogenous Sag result in enhanced selection of Sag-specific regulatory T cells early in life.
In conclusion, we demonstrate that expansion of autoreactive B cells occurred following B cell depletion, and BAFF and autoantigen both may play an important role in the enhanced selection of high affinity autoreactive B cells during B cell reconstitution.
Although selection of antigen-specific regulatory T cells in the thymus upon recognition of the cognate antigen in TCR transgenic mice is a well-established result, our data represent one of the few examples showing enhanced selection of foxp3+ cells due to expression of an endogenous self-antigen in the polyclonal repertoire of normal mice.
Third, advances in chemometric methods can potentially aid in the enhanced selection of virus signal in the presence of a complex background.
This enhanced selection of self-specific foxp3+ T cells will certainly help to decipher signaling events affecting this population during their differentiation.
To avoid enhanced selection of epidemic strains, only one strain per month per hospital was included.
Collectively, the serial passage assay supported the enhanced selection of tumor-initiating cells in the absence of miR-203 upon oncogenic Hras induction.
However, at the transitional B-cell stage this inhibition was reversed with enhanced selection of B cells into the transitional compartment.
A signature of enhanced selection in sympatry vs. allopatry could be due to selective processes or demographic processes (e.g. recent population growth).
On the other hand, since JNK positively regulates thymocyte negative selection [32], the increased JNK activity could be suggestive of an enhanced negative selection in Cdc42−/− thymocytes.
