Similarly, a sub-activating dose of IFN-γ (e.g., 0.05-0.15 µg/L) is able to prime macrophages for an enhanced activity of signal transducer and activator of transcription 1 (STAT1) under an activating dose of IFN-γ (e.g., 0.5-5 µg/L).
We demonstrated that anti-Cripto Mab-induced CEM/A7R cell apoptosis, which was associated with an enhanced activity of the c-Jun N-terminal kinase/stress-activated protein kinase and inhibition of Akt phosphorylation, resulting in an activation of mitochondrial apoptosis pathway as evidenced by dephosphorylation of Bad at Ser136, Bcl-2 at Ser70 and a cleaved caspase-9.
Endurance exercise is well known to enhance the capacity for antioxidant defense, including an enhanced activity of free radical scavenging enzymes (e.g., SOD, glutathione peroxidase, and catalase) and mitochondrial oxidative enzymes (e.g., citrate synthase and NADH oxidase), in both young and old rats [ 26, 27].
An indirect over-expression of Erg8 through an enhanced activity of UPC2 (a global transcription factor regulating the biosynthesis of sterols in S. cerevisiae) for terpenes production has been studied by Ro et al [58].
These results were also consistent with a previous observation that acute activation of the photoactivated adenylyl cyclase PACα in cholinergic neurons evoked an enhanced activity response (Weissenberger et al., 2011).
It was demonstrated that the catalyst has an enhanced activity and sulfur tolerance during naphthalene hydrogenation.
These cooperative effects make g-C3N4/RP-3.18/MoS2-0.52 enhancedactivityced activity.
Only HRP modified with GO-GQDs offers an enhanced activity (more than 1.9 times of pristine enzyme) and thermo-stability.
The ZnO samples, usually possessing a large amount of defects, with a higher crystal quality showed an enhanced activity.
Interestingly, the N159V mutation significantly increased the Km value toward 3-HPA, resulting in a 5.7-fold reduction of kcat/Km, but showed an enhanced activity toward NAD+, largely due to the decrease in Km.
Several clones showed slightly higher activities (kcat/Km) toward either 3-HPA or NAD+ than the wild-type enzyme, but there was no variant having an enhanced activity for both the substrates.
