Sentence examples for an endogenous element from inspiring English sources

It may be possible to set up animal models by expressing HERV sequences under the appropriate conditions, mimicking exposure from an endogenous element.

Once inferred, any endogenous elements can be saved as known ones into a configuration file for future filtering out of undesired reads at the beginning.

F The length of the 5' poly-A tract in each of these insertions is determined by the length of the 5' poly-A tract of the endogenous element that was involved in the recombination event.

Internal regions that are most overexpressed in the pairwise comparisons are ERVL, a very old endogenous element that is found even outside of primates and shows high similarity to foamy retroviruses [ 25] and its younger relative HERVL.

Sequencing of these PCR products and additional PCR experiments (not shown) indicated that these elements had undergone recombinations with an endogenous Zorro3 element located on chromosome R that is 5' truncated and also includes 1.4 kb of inverted Zorro3 sequence.

Evidence of cross mobilization of hobo by an endogenous Homer element emphasises the necessity to understand the endogenous transposons within a species.

The two SNPs that had the strongest association with virologic control were both near HLA-B*57: the first was a SNP in an endogenous retroviral element designated as HLA complex P5 (HCP5), and the second SNP was in the 5'-region of the HLA-C gene [27].

Detailed sequence analysis of the EVADR genomic locus revealed sequence identity with a MER48 LTR, which is an endogenous retroviral element of the ERV1 family [ 54].

Gene disruption is also known to cause spontaneous renal carcinoma in the Eker rat, where an endogenous retroviral element (the rat intracisternal A-particle) has integrated into an intron of the tumor suppressor gene tuberous sclerosis 2 (Tsc2) [ 24– 26].

They identified five new 5′-fusion ETV1 partners including the prostate-specific androgen-induced gene SLC45A3/ Prostein, an endogenous retroviral element HERV-K, a prostate-specific androgen-repressed gene C15orf21, and a strongly expressed housekeeping gene HNRPA2B1.

Interestingly, the work is in line with a previous finding by the authors, also published in Biology Direct, where they also concluded that the downregulation of GABBR1 via an endogenous retroviral element might be the cause of schizophrenia.