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In this study, β-tricalcium phosphate (β-TCP) was used to coat Mg scaffolds in an effort to modulate the detrimental osteoimmunomodulatory properties of Mg scaffolds, due to the reported favorable osteoimmunomodulatory properties of β-TCP.
With the aim of overcoming this tolerance and augmenting immune responses to CRPC tumors, cancer researchers are investigating inhibition of molecules or pathways that dampen immune responses (so-called immune checkpoint receptors), in an effort to modulate the immune system itself to fight cancer 4, 6.
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Still, Mr. Kerry's effort to modulate the tone of a party that has been powered by anger for most of the year, which he expressed last week in an interview and reinforced on Sunday with an orchestrated set of statements by party leaders, showed at least initial signs of success, though even some Democrats were skeptical that it would last through four days of conventioneering.
People are applying transcranial direct current stimulation devices on their heads in an attempt to modulate their mood.
These results clarify the interpretation of accumulated drug binding data and provide a valuable template for design efforts to modulate the interaction with HSA.
Efforts to modulate the β-cell epigenome as a means to prevent, diagnose, and treat diabetes are also discussed.
Some non-Mormons say they sympathize with the church and its efforts to modulate its profile.
While in office, Mr. Gingrich battled efforts to modulate demand through tools like increased gas taxes and tighter fuel standards, and he argues that voters won't support such measures even now.
Although efforts to modulate these interactions are more challenging and much less mature than work on conventional drug discovery pathways, significant progress has been made on several fronts.
The direct identification of drug-binding sites clarifies the molecular mechanisms of important TRPA1 agonists, and will facilitate drug design efforts to modulate TRPA1.
Efforts to modulate the biological activity by structural modifications using synthetic organic chemistry have been difficult because of the complexity of its chemical structure.
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