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Interestingly, at low concentration casCuNPs serves as an efflux pump inhibitor and prevents biofilm formation15.
In fact, OmpW has been associated with EmrE, an efflux pump belonging to the small multidrug resistance (SMR) family9,25.
Lowrence Rene, C. et al. Copper nanoparticles as an efflux pump inhibitor to tackle drug resistant bacteria.
Under normal conditions, an efflux transporter will recognize the dye as a foreign substance and remove it.
An antibiotic resistant cell is a cell that survives antibiotic treatment by carrying a resistance factor (for example, an efflux pump).
Such incontinence may be a dribbling overflow from a permanently distended bladder, or an efflux from a contracted bladder whose outlet is always open.
The outward K+ current is set to be 5 nA with duration of 3 ms, which equals to an efflux of 1.55e-16 mofe of K+.
P-glycoprotein is an ABC protein that functions as an efflux pump for multiple drugs, natural products and peptides.
This report describes an efflux transport method using dynamic dialysis to study the liposomal membrane permeability of hydrophobic compounds.
It was postulated that cues inducing lysosomal stress, including starvation and physical exercise, activate MCOLN1, resulting in an efflux of Ca2+ from the lysosome, a cytoplasmic increase in Ca2+ concentrations and consequent activation of calcineurin.
A transmembrane protein, Pgp acts as an efflux pump and reduces intracellular drug levels and thus its effectiveness as an antitumor agent.
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CEO of Professional Science Editing for Scientists @ prosciediting.com