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In an attempt to characterize pulmonary vs. systemic side effects preclinically, we chose the acute lipopolysaccharide (LPS -induced infLPS -induceddel inflammationn efficacy model and also to set doses for multinle-dose side effect studies.
The aim of this study was to evaluate the diagnostic efficacy of cone-beam computed tomographic (CBCT) imaging in endodontics based on a systematic search and analysis of the literature using an efficacy model.
Likewise, disease-specific DPCO models may become available that potentially allow informing an efficacy model across different drugs, as was demonstrated for colorectal cancer.
24 25 This was a large trial evaluating the effect of the Integrated Management of Neonatal and Childhood Illness strategy conducted at scale under programme conditions through the existing district health system, unlike in an efficacy model in a resource intensive setting.
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Perez et al. [10] developed a luminous efficacy model for all sky types as a function of the solar zenith angle (Z), atmospheric precipitable water content (W), and the sky brightness index.
The optimal doses of Ad5mir122 and Ad5WT were determined in order to define a protocol that would allow repeat delivery in a cancer efficacy model.
A luminous efficacy model was integrated in the analysis of data.
Natural resource managers require a fire efficacy model that accurately predicts juniper mortality rates and is based entirely on predictors that are measurable prefire.
This paper aims to evaluate the global and diffuse luminous efficacy based on the measured horizontal daylight illuminance and on solar irradiance data and to propose a luminous efficacy model.
Differentiation based on PK profiles in multiple species as well as activity in a chronic efficacy model led to the identification of 1 (CC-930) as a development candidate, which is currently in Phase II clinical trial for IPF.
Optimized indole GSM 29 exhibited good alignment of in vitro potency and physicochemical properties, and moderate reduction of brain Aβ42 was achieved in a rat efficacy model when dosed orally at 30 mg/kg.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com