Sentence examples for an effect of the mutation from inspiring English sources

In contrast, the mutant R1242G showed depolarization-induced outward omega currents carried by caesium that were small or absent in wild-type or in untransfected myotubes which we interpret to be an effect of the mutation (Fig. 3A and B).

Significance of any of the genetic terms (G, G ×  S, G ×  E, G ×  S ×  E) indicates an effect of the mutation on MET in at least one condition and shown with the color bar at the bottom of Fig.  4a.

The patient whose uveal melanoma carried the TERT mutation is free of disease at 31 months after diagnosis but an effect of the mutation in the TERT promoter on the metastasis risk cannot be definitely excluded.

Furthermore, there was also relative sparing of hearing loss at 16 kHz in the C57BL/6 background, but this may be due to the relatively poor hearing of the wild-type strain at 16 kHz rather than to an effect of the mutation.

A schematic diagram of the time course of tau mRNA and protein expression is shown in Supplementary Fig. 4. The shortest 0N3R and 1N3R tau isoforms were relatively less abundant in the N279K mutant neurons compared to the control and P301L neurons, suggesting an effect of the mutation on the splicing of 3R tau isoforms.

The reason for this is unknown, but may be due to an effect of the mutations on protein stability.

Therefore we did not expect an effect of the mutations in the maltose-maltodextrin utilization system on the multiplication of L. monocytogenes within Caco-2 enterocytes, which are known to contain rather large amounts of glycogen.

We also confirmed that the suppressed effect of Hcrt overexpression on sleep in dbh and hcrtr mutants is not due to an effect of the mutations on the efficacy of the HS overexpression system.

Thus we might have expected an effect of the Kir6.2-V59M Kir6.2-V59M atrial function.

Then, an effect of the ssa2 mutation on tRNA import was assessed under the conditions of nutrient starvation.

Mutant idn2 8 transcripts accumulate to similar levels as IDN2 transcripts (Fig. S5A ), pointing to an effect of the idn2 8 mutation at the protein rather than the mRNA level.