Sentence examples for an effect of mutations from inspiring English sources

To test the possibility that the observed changes in Vmax are due to an effect of mutations on the binding of coupling ions, we have performed uptake of 100 μM Pi in the presence of various concentrations of NaCl (0−25 mM) in those mutant strains, which show detectable levels of activity (Supporting Information Figure S6).

(A ) Effect of mutations on affinity for ribosomal anti-Shine Dalgarno sequence.

There was also no compelling evidence for an effect of mutation position on risk associated with AR CAG repeat length.

Importantly, however, we did observe an effect of mutation of the SUMOylation consensus site surrounding K402 on Ago2-dependent siRNA activity.

Because neither Glu218 nor Glu305 has direct contact with bound MgATP in the BC domain active site, the lack of an effect of mutation of these residues on MgATP binding is not unexpected.

While resistance to EGFR antibodies is associated with mutations in the KRAS gene, an effect of BRAF mutations has not been proven conclusively [ 11].

However, an effect of these mutations on alternate mGluR1 signalling pathways has not been excluded [33].

The reason for this is unknown, but may be due to an effect of the mutations on protein stability.

Possibly, higher exposure or a longer duration is needed to reveal an effect of FLG mutations.

In that study, an effect of FLG mutations irrespective of AD (OR 1.69595% CI 1.0 2.6) was found 34.

The fact that we could not show an effect of FLG mutations in the present study was unexpected.