Sentence examples for an effect of mutation from inspiring English sources

There was also no compelling evidence for an effect of mutation position on risk associated with AR CAG repeat length.

Importantly, however, we did observe an effect of mutation of the SUMOylation consensus site surrounding K402 on Ago2-dependent siRNA activity.

Because neither Glu218 nor Glu305 has direct contact with bound MgATP in the BC domain active site, the lack of an effect of mutation of these residues on MgATP binding is not unexpected.

Amino acid 878 is located at the extracellular linker between transmembrane S5 and S6 in domain II (DII) of the Nav1.5 protein (Fig. 2c), which forms part of the channel pore, consistent with an effect of mutation R878C on permeation through Nav1.5 channels.

(A ) Effect of mutations on affinity for ribosomal anti-Shine Dalgarno sequence.

Consistent with an effect of this mutation on NuA4 function, Tra1-F3744A reduced histone H4 acetylation of the PHO5 promoter.

While resistance to EGFR antibodies is associated with mutations in the KRAS gene, an effect of BRAF mutations has not been proven conclusively [ 11].

However, an effect of these mutations on alternate mGluR1 signalling pathways has not been excluded [33].

The reason for this is unknown, but may be due to an effect of the mutations on protein stability.

Possibly, higher exposure or a longer duration is needed to reveal an effect of FLG mutations.

In that study, an effect of FLG mutations irrespective of AD (OR 1.69595% CI 1.0 2.6) was found 34.