Only two PM patients had more than a single affected muscle fiber, but both patients were older than 65 years, and in these cases, the COX-negative fibers may be considered an effect of ageing.
It is unclear whether the change in triglycerides is attributable to the menopausal hormonal transition or is an effect of ageing or lifestyle changes among postmenopausal women.
In conclusion, this cross-sectional study shows an effect of ageing on cystatin C levels in those without overt vascular disease or diabetes.
28 Horne et al 27 reported fatalistic beliefs in older Caucasian as well as in South Asian people, including older Chinese people, who accepted falls as inevitable and an effect of ageing rather than a metaphysical consequence.
This suggests that there is an effect of ageing on RSFA with a neural origin, which should increase with age, despite the observed overall age-dependent decrease in RSFA.
However, some differences could also be an effect of ageing where muscle fibres are often replaced by fat and connective tissue [ 25] as differences were also present between the patient's non-affected supraspinatus muscle and the vastus lateralis and the muscles in the healthy participants.
