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Dalbavancin did not have an effect on the QTcF interval, and an effect exceeding 10 ms could be excluded at all time points after a single i.v. dose of 1000 mg and 1500 mg.
The capacitance of auxiliary cells Ca has an effect exceeding 10 ms on rise and fall of SP only for large values, over 50 pF (Fig. S2C, D).
The conductance of the auxiliary cells Ga exerts an effect exceeding 10 ms on both rise and fall of SP only if it becomes small, less than 1 nS (Fig. S2A, B).
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It requires review of only those rules with a yearly effect exceeding $100 million: a dozen or so regulations a year.
At either a T or S dose of E, a QTc effect exceeding 5 ms could be excluded.
Often, researchers bypass them and test in vivo effects of drugs loaded in DDS characterized only with a variable degree of scrutiny in vitro, betting that observation of a desired effect exceeding that of "untargeted drug" provides a mandate to publish "proof of concept" papers.
Four of nine items had a floor effect exceeding 25%, with more than 65% of patients reporting no vomiting (97.1%), no blood in bowel movement (76.5%), and no nausea (60.9%).
It is also noteworthy that QTcF, which uses a fixed correction factor, was comparable with methods derived from the study data (QTcI and QTcP) and that a QTc effect exceeding 10 ms could be excluded with all correction methods.
The risk that seed collection will have a negative effect exceeding the benefits gained through directed dispersal of seed and facilitated establishment of seedlings is of concern only for some species, particularly those with small populations.
Cortes et al. [ 5] have demonstrated a secondary association effect, exceeding the genome-wide significance threshold, at three correlated HLA-A markers (e.g., HLA-A*02 01; HLA-A*02 01nd P = 1.41 × 10−9) after cORtrolling for the association of HLA-B alleles.
For cracks and notches the net section strength showed a notch-strengthening effect, exceeding the tensile strength of the intact honeycomb and increasing with crack or notch depth.
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