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Taken together, these results point to the possibility that immunodetection of the 85 90 kDa palladin isoform in samples collected by EUS-guided fine-needle aspiration may have diagnostic utility as an early, specific marker for the development of pancreatic adenocarcinoma, which may provide new avenues for diagnosing pancreatic cancer at a treatable stage of the disease.
Instead, these animals are characterized by an early specific deficit in the differentiation of the Sst-expressing interneurons, which are likely to be implicated in the pathophysiological mechanisms of epileptogenesis.
In patients with clinically suspected acute viral induced myocarditis, there is no definitive clinical indication to perform EMBs, because there are no data that an early specific treatment has any benefit concerning duration of the disease or improvement of heart failure.
Because such deficits in visual attention are neither universal nor specific in autism, other researchers have proposed that an early specific deficit in orienting to socially relevant stimuli may be a necessary condition but probably not sufficient for autism to emerge.
An early specific effect of chloride ions on the heterogeneous swelling at the metal-polymer interface in non-defective coated metals is elucidated using frequency-dependent alternating-current scanning electrochemical microscopy (AC-SECM).
An early specific cellular response to DSBs in mammalian cells is the phosphorylation of the histone protein H2AX (γ-H2AX), with respective foci formation.
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Thus, the medial orbitofrontal cortex appears to exhibit a very early specific neural signature or specific pattern of activity in response to infant faces.
The main reason for the poor rate of survival is that there is a lack of early specific symptoms and most of the patients have advanced stage disease (FIGO stages III and IV) at diagnosis.
In conclusion, a complete microbiological workup leads to an early and specific diagnosis.
Their correct application requires an early and specific diagnosis of IA, which is still not properly achievable.
Clinically, it is desirable to rely on an early and specific marker for final neurological outcome.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com