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The dataset for the current analyses is the same as that for the 2008 main results paper, which includes all randomized participants from enrollment until 10 December 2007, an average trial follow-up of 3.5 years (5).
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An average trial-to-trial change in firing rate was calculated for each cell, and then all cells were averaged to complete one run of the bootstrap.
Third, an analysis on average trial velocities was performed.
To calculate ERPs, the raw data were filtered from 1 8 Hz, a 200 ms baseline was subtracted from each trial, and an average over trials was calculated for each participant (Szczepanski et al., 2014).
All rats had an average per trial latency to reach the platform of less than 10 s by the end of the third habituation session.
While this type of averaging is not physiologically relevant in the sense that populations carry out working memory each trial, and not as an average across trials, it does represent the typical averaging carried out to characterize cell behavior in studies of working memory (i.e. average PSTH histograms across trials determine cell pattern type).
Each mouse received four training trials per day with an average inter-trial interval of 15 min.
The analyses summarized in Fig. 4 and Table 1 represent just 487 trials amongst 64 participants – each participant thus contributed an average 7.6 trials to the analysis.
The measured performance is an average across trials whose reports are flanker and target based.
Although binding could capture the experience of individual actions and their effects (Walsh and Haggard, 2013), it is measured as an average across trials.
Thus the remaining seven child subjects were included for analysis, with a total of 11 useable trials (an average of 1.6 trials per subject).
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