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Doing this would yield an average divergence of 1.8% per Myr (median: 1.2% per Myr), which is slightly less than the popular 2%.
We identified high levels of DNA polymorphism in R. etli, and found that there was an average divergence of 4%to6%6% among the tested strain pairs.
This conclusion is strongly supported by the presence of a highly heterozygous genome in which one of the haplotypes is largely similar to the Type 1 sequenced isolate, whereas the other haplotype, which contains the Type-1 defining MAT and ITS loci, has an average divergence of 5%.
Similarly, the phylogenetic analysis of 391 nt from the nucleocapsid 1 region of 5 HBoV3 isolates from Chile revealed an average divergence of 1.2% (range 0%1.6%%), and the phylogenetic tree analysis showed that the isolates grouped into 2 clusters with no evident temporal clustering.
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All Ks values gave an average divergence estimate of 34.75 Mya.
The analysis gave an average divergence rate of 0.8% per million years with our in-group and the K81uf model of evolution.
Assuming an average divergence time of 140 MYA and that rates were equivalent along both lineages, we inferred an average rate of 0.68 × 10-9 (95% CI = 0.67 × 10-9, 0.69 × 10-9) substitutions per site per year at synonymous sites (μS, see Table 1).
The B-index is an unbiased estimator of the average divergence of a family of sequences from its last common ancestor (root) that takes into consideration the correlations among sequences determined by their phylogenetic tree.
These proviral-partial copies contribute substantially to an increase in the average divergence of the Ty3/gypsy complement (Tables 2 and 3).
Assuming an average DNA divergence of 6.5 million years between the human and chimpanzee genomes (52), this results in a point estimate for the average divergence of Neandertal and modern human autosomal DNA sequences of 825,000 years.
This variant was related to RABVs found in bats of the genera Histiotus, Nyctinomops, and Tadarida from Chile and Brazil but appears to be an independent lineage; its branch length and pairwise average divergence of 5% separate it from its closest relatives.
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