Sentence examples for an augmented sensitivity of from inspiring English sources

That is, when AT2 receptors were exogenously activated or when the counterbalancing actions of AT1 receptors were blocked, an augmented sensitivity of the high-pressure baroreceptors became evident.

Indeed, the augmented coronary reactivity of the HF rats was due either to an augmented sensitivity of the SMCs to NO in the rats displaying body weight gain compared to the control ones or to an improved ECVA in the animals with no body weight gain.

Treatment of MCF-7 breast carcinoma cell line with antagomiR-451 via transfection and doxorubicin revealed an augmented sensitivity to the drug uptake [ 81].

Here we show that the proautophagic proteins Ambra1 and Beclin 1, involved in the initial steps of autophagosome formation, are highly expressed in the adult subventricular zone (SVZ), whereas their downregulation in adult neural stem cells in vitro leads to a decrease in cell proliferation, an increase in basal apoptosis and an augmented sensitivity to DNA-damage-induced death.

These effects ultimately lead to an augmented sensitivity.

The augmented sensitivity of cisplatin-resistant cells to TRAIL (TNF-related apoptosis-inducing ligand) signaling results from the redistribution of the death receptor 4 (DR4) to lipid raft subdomains within the plasma membrane.

The deficiency of vitamin E led to the retina degradation, the augmented lipofuscinogenesis in RPE, the decrease in the PUFA level in rod outer segments and RPE as well as the augmented sensitivity of the retina to photo-oxidative damage (Hayes 1978; Farnsworth et al. 1979; Beatty et al. 2000).

Reduced NE-induced constriction in BHR may result from augmented sensitivity and number of β-2 adrenergic receptors due to elevated corticosterone [ 59] which may blunt α-1 adrenergic receptor-mediated constriction.

In concordance with the augmented sensitivity to CDDP, the density of DNA adducts was higher in HUH6 cells compared with HepT1 cells and increased in both lines with exposure time and drug concentration.

The augmented sensitivity to TRAIL resulted from the redistribution of DR4 (but not DR5) and the various DISC components to lipid raft subdomains of the plasma membrane in cisplatin-resistant cells.

Overall, we observed three different phenotypes that were associated with the presence of p53: reduced, unchanged or augmented sensitivity for extrinsic cell death induction by TRAIL.