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However, analysis of the CP sequences from five WANA countries revealed a geographically associated variation among CpCSV isolates.
In conclusion, our data indicate the existence of a geographically associated variation in the molecular, serological and presumably biological properties of CpCSV.
In this paper, we provide evidence for the occurrence of CpCSV in countries other than Ethiopia and for the existence of a geographically associated variation among CpCSV isolates differing not only in CP (molecular and serological) properties but presumably also in virulence.
Because of the serological and molecular variability observed for FBNYV-like isolates from Ethiopia and other countries, Franz et al. [ 13, 16] and Katul and Vetten [ 25] explained such observations as a geographically associated variation among FBNYV-like nanoviruses from different countries.
The Moroccan FBNSV isolate Mor5 was genetically quite distinct from the Ethiopian FBNSV isolate, from which it was serologically (and in coat protein sequences almost) indistinguishable, thus providing again an indication of a possible geographically associated variation among isolates of a nanovirus species.
Fig. 1 Average values and associated variation for seven landscape metrics across six spatial extents.
This area has previously been suggested to display selection pressure associated variation [ 11].
Transfer was done by applying a majority rule: when the top scoring protein p had a number of cancer associated variations higher than that associated to "other diseases", all the variations of the query protein q were labelled/predicted as cancer associated; otherwise all the variations of the query protein q were labelled/predicted as "other diseases".
This is so particularly for cancer associated variations [ 7- 9].
Furthermore, men and women associated variations in blood-glucose levels to other behaviors, particularly food selection.
Annotating the diseases associated variations on different levels are necessary to identify the outstanding risking genes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com