The similarity of the three largest membrane-bound subunits of Complex I is an intriguing aspect of its function.
While regulation of auxin level and distribution is an important aspect of its function, the ability of auxin to regulate cell elongation also depends on developmental context and the status of other hormonal and environmental signals (Stewart and Nemhauser, 2010; Del Bianco and Kepinski, 2011).
Membrane association is thought to be an important aspect of its function since α-syn is associated with cellular membranes [ 6, 17, 18] with approximately 15% bound to membranes in rat brain homogenates [ 19] and 20 25% associated with membranes in cell culture models [ 18]. α-Syn interacts with lipid rafts [ 20], lipid droplets [ 18] and with mitochondria membranes [ 21, 22].
The findings support the hypothesis that the capacity of TRPC5 to be stimulated by agents acting at its turret is a crucial aspect of its function in mammalian biology.
Because the nervous system is a biologic electrochemical complex, it is possible to regard every aspect of its function as an electrical manifestation, but it is primarily the epilepsies that are regarded as expressions of disordered electrical activity.
Other cell types may respond to an AFG3L2 altered function with a different efficiency and looking at mitochondria as an integrated subcellular system, each aspect of its function can be potentially impaired: bioenergetics, trafficking, organelle interconnectivity (fission/fusion) and protein quality control.
Contemporary dissections of the heart show he was correct on many aspects of its functioning.
These data therefore indicate that likely the ubiquitylation of ERCC1, which is reversed by USP45, controls an aspect of ERCC1 function other than regulating its stability.
Their failings have even been accepted as an aspect of their function.
Primary outcome is socialization, as an aspect of adaptive functioning.
Working memory is an aspect of executive function.
