Malonyl-CoA is the limiting precursor for the overexpression of an array of heterologous pathways in bacteria, such as flavanones, polyketides, microdiesel and poly-unsaturated omega-3 fatty acids.
They contribute to an array of physiologic pathways, the complexity of which is still being investigated.
Protein kinases regulate an array of signalling pathways that control metabolism, cell cycle progression, cell death, differentiation and survival.
Among the targets, damage to DNA integrity is critical and elicits a global stress response that is characterized by activation of an array of signaling pathways.
Given the fact that FGFRs activate an array of signaling pathways, it is crucial to have a regulatory system in place to circumvent unnecessary signal transmission.
The master kinase protein kinase C-α (PKCα) is targeted by Ca2+ to the plasma membrane where it is activated by a specialized set of lipids and second messengers, thereby triggering its essential functions in an array of signaling pathways.
In addition to triggering NF-κB activation, RAGE engagement by its myriad ligands is linked to an array of signaling pathways, including MAPK family members, such as Jun-N-terminal kinase (JNK), p38 and extracellular signal-regulated kinase (ERK), PI3K/Akt, Rho GTPases, Jak/STAT and Src family kinases [ 7].
We have generated an exhaustive assembly of the transcriptomes of two species of theridiid spider and been able to identify homologues to an array of pigment-pathway genes from D. melanogaster.
Alcohol has an array of molecular pathway targets and modes of inducing apoptosis and the candidate disease genes selected using this method have a strong role to play in apoptosis.
