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In cancer, an array of molecular abnormalities leading to the modulations in expression of key proteins important in the cellular signaling pathways and cell proliferation has been identified.
Mass spectrometry analysis revealed that complete BBI was composed of an array of molecular masses, whereas mature BBI showed the presence of a major peak of the expected size.
There are many evidences that preferential invasion of the peritoneum by ovarian cancer is not only due to anatomic proximity but also to an array of molecular signals secreted by cancer cells and stromal cells predisposing the peritoneum to invasion.
A clear link between C-Frag and diverse system stresses generated from an array of molecular mechanisms is shown.
Thus, polyploidy in the plant kingdom may involve an array of molecular events that are dependent on the genomic context.
Plants respond and adapt to drought stress conditions with an array of molecular, biochemical, and physiological alterations.
Similar(46)
Putative intermediate metabolites include an array of low molecular weight and high molecular weight thiols, nitrosoglutathione, nitrosohaemoglobin and nitrosoalbumin, some of which might be present in sufficient quantities to exert biological effects [ 37- 41].
In the past 2 decades, expansion in the knowledge of molecular medicine and genomics has revealed an array of new molecular targets that are being harnessed for the design of new therapies in oncology.
Moreover, CYLD induced an array of other molecular changes associated with modulation of the "malignant" phenotype, including a decreased expression of cyclin D1, N-cadherin, and nuclear Bcl3, and an increased expression of p53 and E-cadherin.
We have focused on urinary proteome analysis as the urinary proteome has been found to be quite stable [16], [17] and contains an array of low molecular weight proteins and peptides that can be analyzed without the need for additional manipulation such as proteolytic digests [18].
C-Frag, a main phenotype of MCD, is achieved through an array of individual molecular mechanisms, including centrosome amplification.
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