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The antitumor activity of these new compounds against an array of cancer cell lines (human colon carcinoma (HCT116), leukemia (K562), and breast cancer (MDA231) was evaluated.
Identifying an array of cancer genes in sick children could serve many purposes.
Our estimates are also generally consistent with the number of 10,000 mutations per cell arrived at experimentally by Stoler et al. [19] They are also concordant with the range of frequency of "passenger" somatic mutations observed by Greenman et al. in an array of cancer genomes [20].
This research aimed to determine the real-world perspectives of an array of cancer care providers in a wide range of care settings.
We believe that our finding of Sox2 regulating an array of cancer- and stem cell-associated genes provides a mechanistic explanation as to how Sox2 enhances stemness and tumorigenesis in cancer cell subsets.
This trend is particularly evident in the field of positron emission tomography (PET), in which a wide variety of effective antibody-based radiotracers have been developed against an array of cancer biomarkers.
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Clearly there is a lot still to be done — in curbing tobacco use, preventing exposure to carcinogens and detecting and treating an array of cancers.
The medication, called Vitrakvi, is the second treatment to receive FDA clearance based on a common biomarker found in an array of cancers.
Other companies, including Myriad itself and Ambry Genetics, along with academic medical centers, have jumped in with panels of dozens of genes linked to an array of cancers.
In each case, activation of these proteins and pathways is known to contribute to the development of an array of cancers [25], [26], [27].
Like FAS, ID over-expression correlates with tumor development in an array of cancers [ 40, 41], and knockdown of ID2/ID3 induces growth arrest and apoptosis [ 39, 42].
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