A less arbitrary variant on this approach defines the cut-off in order to produce a high specificity among an unexposed population and then increases the calculated prevalence of infection by a factor derived from the observed sensitivity of the chosen cut-off in a population of patients with proven tuberculosis, who must therefore already have tuberculous infection [12].
Previously described methods for the combined analysis of common and rare variants have disadvantages such as requiring an arbitrary classification of variants or permutation testing to assess statistical significance.
A single mutational step from the wild type is sufficient to confer resistance/viability in the novel environment, but this step can land on an arbitrary set of distinct variants, characterized by a distribution of growth rate, reproductive variance and selective disadvantage in the original environment.
In this section, we describe how a single reference genome can be augmented with genomic variant information gathered from an arbitrary collection of genomes.
Starting with the constitutively active variant (CaMKIIT286D), we replaced residues 302 to 313 in the R3 element by an arbitrary linker sequence that is not expected to form regular secondary structure.
Therefore, we have slightly modified the HyBR code in order to support real spatially variant PSFs in an efficient way, even with an arbitrary number of PSFs.
The material point method is a variant of the finite element method formulated in an arbitrary Lagrangian Eulerian description of motion.
The SNPs in A. glycines B1 454 data were predicted by gsMapper program (Roche) with an arbitrary criterion of at least 4 reads supporting the consensus or variant.
SNPs in the library were predicted using gsMapper software (Roche Diagnostics) with an arbitrary criterion of at least 4 reads supporting the consensus or variant.
SSRs were identified using Msatfinder version 2.0.9 program [93] whereas SNPs were predicted using gsMapper software (Roche Diagnostics) with an arbitrary criterion of at least 4 reads supporting the consensus or variant.
