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Finding an appropriate exposure that might be particularly harsh for the stone. .
This task is made challenging due to the large size of the rain sensors (26 cm × 26 cm × 26.7 cm), Finding an appropriate exposure that might be particularly harsh for the stone.
We suggest that the present mechanistic assessment framework can be used to assess exposure risk to environmental pollutants in polyculture systems and provide an appropriate exposure analysis to improve decision-making in the design and development of effective aquaculture systems.
Hence, the first methodologic issue is the choice of an appropriate exposure marker for MeHg.
We used the AIC value to select an appropriate exposure lag period.
Having confirmed that Drp1 levels are increased in SN neurons, we sought to match an appropriate exposure duration in vitro.
Similar(47)
If the effects are ascribed to the unmeasured parent compound, toxicokinetic calculations may perhaps be applied to generate a more appropriate exposure measure that reflects the exposure to the active substance.
This is, to our knowledge, the first study to separate the effects of recent versus habitual alcohol exposure, and as the duration of spermatogenesis is approximately 72 days 30 the typical intake is probably a more appropriate exposure measure than the intake during the week preceding the delivery of the semen sample.
It is considered a more appropriate exposure measurement for the assessment of dose safety relationship instead of the actual dose, since patients received the scheduled dose before neutropenia occurrence, while the actual dose is resulted from dose delay and dose reduction after AE occurrence so may be confounded for dose neutropenia assessment.
The ARTEMIS mean exposure was deemed an appropriate target exposure given the demonstrated efficacy and safety in this trial, 7– 9 and that pharmacokinetic extrapolation from adults to pediatrics is considered sufficient with regard to antiretrovirals.
This maximized possible infant exposure to thimerosal while still maintaining an appropriate clinical exposure.
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