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Interestingly, an approach to generate replication-defective vectors from MVA has not been pursued.
Features: provides a survey of resilience methods and performance models; examines the various sources for errors and faults in large-scale systems; reviews the spectrum of techniques that can be applied to design a fault-tolerant MPI; investigates different approaches to replication; discusses the challenge of energy consumption of fault-tolerance methods in extreme-scale systems.
Two main approaches to replication can be distinguished: master slave and multi-master replication.
The modifications of the method with extracts tailored for the detection of different kinds of DNA synthesis errors could be applied also as a simple approach to monitor replication fidelity in cell extracts.
An alternative approach to identifying replication origins used genome-wide location analysis to determine the positions of ORC and MCM proteins [ 24].
An alternative approach to the replication of the complete virus and the processing of virions for influenza vaccines is the exploitation of recombinant technology.
Our results demonstrate that vector-mediated delivery of shRNA expression cassettes targeting the structural B19-VP2 gene is a suitable approach to inhibit B19V replication.
A second approach to inhibiting PV replication is by targeting the virus-encoded proteases 2A and/or 3C.
Here, we applied a related approach to characterize chromosomal replication origins and termination sites in C. glabrata.
The microRNA-based gene-silencing machinery has been recognized as a promising approach to control viral replication and used for improving safety for the live attenuated virus vaccines.
The only diagnostic approach to identify replication-competent poxvirus particles is their propagation in a suitable cell culture system.
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