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An application for sequencing a transcriptome to resolve the gene context of an unknown genome is also available.
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The recent development of high-throughput sequencing (HTS) and its application for sequencing the exomes or genomes of thousands of people (including participants of the 1000 Genomes Project) has provided experimental evidence of the extensive variability of the human genome (both in single nucleotide polymorphisms (SNPs) and copy number variations (CNVs)).
Slider is an application for the Illumina Sequence Analyzer output that uses the probability files instead of the sequence files as an input for alignment to a reference sequence or a set of reference sequences.
Lu [16] presents an application for processing gene sequences on the Cloud.
Tandem Repeats Finder is an application for finding tandem repeats in DNA sequences, that employs a stochastic model of repeats and associated statistical detection criteria.
For illustration, an application to sequencing optimization for heterogeneous cold-standby system is given; a modified genetic algorithm is developed to solve the proposed optimization problem with interval-valued objective.
J. A. D. and R. H. B. Jr. are employed by the University of Massachusetts Medical School and co-inventors on a patent application for antisense sequences and exon-skipping technology targeting dysferlinopathies.
An application to a sequencing study for non-syndromic cleft lip with or without cleft palate (NSCL/P) demonstrates its practical relevance.
The complete conservation of these immunologically relevant sequences through the entire recorded WNV history suggests they will be valuable as components of peptide-specific vaccines or other therapeutic applications, for sequence-specific diagnosis of a wide-range of Flavivivirus infections, and for studies of homologous sequences among other flaviviruses.
We have created an integrated desktop application for short sequence motif analysis.
Software applications for sequence database partitioning, guide tree estimation, molecular classification and alignment acceleration have benefited from embedded k-mer searches as sub-routines.
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