As a surrogate for the concentrations of unbound drug at target sites, CSF concentrations are often used and considered appropriate [ 16, 83], however, a generally applicable relationship between CSF and brain ECF concentrations is questionable [ 5, 15, 17, 134].
In short, it has been concluded that a generally applicable relationship between CSF concentrations and brain extracellular fluid (ECF) concentrations does not exist due to qualitative and quantitative differences in processes that govern the pharmacokinetics (PK) at these sites.
providing a relationship between applications.
To be applicable to various lithologies and porosity ranges, a new relationship between the static and dynamic Young's modulus is being proposed.
PCC is applicable only when we wish to measure a linear relationship between two variables and the variables are from bivariate normal distributions.
Our results suggest a framework to relate structural heterogeneity to functional diversity and, beyond neural dynamics, are generally applicable to the relationship between structure and dynamics in biological networks.
Study results were not applicable for the relationship between the remaining physical environmental factors and total walking and cycling due to a lack of sufficient individual studies in these categories.
Banavar, Maritan and Rinaldo [22] derived a general relationship between size and flow rates in general networks with local connectivity which can predict scaling relations applicable to all efficient transportation networks.
With plausible assumptions about the general form of the potential function, it is possible to calculate a relationship between τ and E that is applicable to all alpha emitters.
There exists a symbiotic relationship between Boris and Harry.
However, in utero poor nutrition status may not be applicable to normal and high birthweight babies; thus, the reported linear inverse association of birth weight with BP may not describe a precise relationship between these two variables.
