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An antiretroviral agent that targets an alternative stage in the lifecycle of HIV with optimal reductions in viral load, and good tolerability with few short- and long-term toxicities, would have a significant impact on the prognosis of treatment-experienced patients.
Geneva converted this industrial landmark into an alternative stage for lyric theater in 1997, but kept some of the brightly painted machinery in the lobby.
Chadwick had worked with an alternative stage group in Gaza called Theatre for Everybody, who performed War and Peace, adapted from Tolstoy's novel and translated into Arabic, showing to hundreds at Al-Mishal in 10 performances throughout 2015.
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With the assistance of the ESA European Space Operations Center this design environment has been extended to cover exploration missions involving the areas of the collinear Earth Moon and Sun Earth libration points, which are of interest as an alternative staging location to the low lunar orbit approach for lunar exploration and for satellite servicing missions, respectively.
Magnetic resonance tomography imaging (MRI) as an alternative staging procedure to CT scanning should be reserved to selected patient populations (e.g. intolerance to intravenous contrast agents) and to institutions with special expertize using MRI (supplementary material S5, available at Annals of Oncology online).
Moreover, it regulates the entrance and exit into an alternative developmental stage, the diapause stage, characterised by extremely high resistance and survival to harsh conditions [20].
Additionally, eight ionization chambers were constructed to be used as an alternative ΔE stage or, in conjunction with the entire DSSSD array, to build up more complex triple telescopes.
In response to adverse environmental conditions, C. elegans larvae undergo developmental arrest in an alternative larval stage known as dauer (Riddle 1988).
Graziano (24) has proposed an alternative fifth stage, the 'Age of Obesity and Inactivity', in which increasing levels of weight gain and obesity alter the pattern of NCDs among the elderly (represented by Olshansky and Ault's fourth stage).
Faced with adverse environmental conditions, C. elegans larva enter an alternative developmental stage known as dauer, dopamine has also been implicated in reducing locomotor output and causing the characteristic quiescent states of these animals.
To identify components of this parallel DAF-16/FoxO regulatory pathway, we exploited the fact that in larvae, DAF-16/FoxO promotes developmental arrest in an alternative larval stage called dauer that is morphologically distinct from reproductively developing larvae [ 32].
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