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In addition, chronic abuse of substances leads to an altered set point across multiple systems.
Persistent challenges to an organism through chronic substance use may ultimately lead to an altered set point across multiple systems.
Chronic, heavy use of ethanol produces an allostatic state wherein reinforcing and stress-provoking effects of the drug battle and oppose each other but generally contribute to an altered set point below that associated with normal mood states.
While breathing air, average arterial P co 2 was significantly lower in the Chuvash polycythaemia patients, indicating an altered set point for respiratory control in the direction of an elevation in pulmonary ventilation.
If replicated, our results imply that these loci not only influence FPG levels, probably through an altered set point for glucose at which an insulin response is elicited, but also jointly increase the risk of type 2 diabetes and the age at diagnosis.
In addition to involving an expanded set of plaintiffs and defendants, an altered set of elements, and the aggregation of claims, FOTM class actions involve defendants with different motives, raise different stakes, and create different incentives to sue and settle than existed in the early years of private Rule 10b-5 enforcement.
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But if a newer, better and perhaps even more complex form of that structure should evolve, suiting the descendant species even better to a slightly altered set of environmental circumstances, it will be conserved.
Based on these experiments, the general idea is that when a group of cells separate from an existing cell layer, the segregating cells express a qualitatively or quantitatively altered set of cadherin family members.
Hierarchical clustering using the significantly altered set of 10 miRNAs showed a clear separation between alive and dead subjects).
The altered set-up may have put HMV on a surer footing, but some analysts argue that the retailer is not out of the woods.
Calculation of the flux distribution with randomly altered set-point concentration values was repeated in 1000 trials.
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