Sentence examples for an alteration in structure. from inspiring English sources
These methylation changes can result in an alteration in structure and function of DNA, such as unwanted activation of repeat elements, abnormal transcriptional regulation of genes involved in cancer initiation and progression, and predisposition to genomic instability through disruption of chromosome replication control [ 2, 3].
Conclusions: Alterations in systemic vascular resistance associated with compromised pregnancies are unlikely to result from or produce an alteration in the structure of omental small arteries.
Carbon sequestration from P. antarctica blooms may influence the carbon cycle in the Southern Ocean, especially if projected climatic changes lead to an alteration in the structure of the phytoplankton community.
It is widely believed they create or promote an alteration in chromatin structure that represses transcription, but their mechanism(s) of action remain enigmatic[1] [4].
Inducible gene transcriptions are associated with an alteration in chromatin structure, which renders the DNA accessible to the transcription factors [30].
These results suggest that torsinA plays an important role in the development of the cerebellum, and that a loss of this function in the Purkinje cells results in a cell autonomous effect leading to an alteration in dendritic structure.
These results suggest that the torsinA is important for the proper development of the cerebellum and a loss of this function in the Purkinje cells results in an alteration in dendritic structure.
The requirement for the histone replacement activity of SWR1 prompted us to look for an alteration in chromatin structure associated with htz1Δ and to determine its dependence on Swr1.
Comparative analysis of the simulations indicates that topotecan produces a different behavior of the protein collective motions and an alteration in secondary structure and flexibility in regions that are not in direct contact with the drug, such as residues 633 643, between the linker and the core domains.
It can cause an alteration in liver structure that may lead to excessive deposition of ECM, apoptosis of hepatocytes and inflammation [ 2, 3].
These abnormalities result from an alteration in chromatin structure, a higher rate of conversion of double-strand breaks (DSB) to chromatid breaks or from deficient DNA repair (Radford, 2004).
