The phrase "an advanced grade" is correct and usable in written English.
It can be used when referring to a higher level or quality of grading, often in an academic context.
Example: "To qualify for the scholarship, students must achieve an advanced grade in their final exams."
Alternatives: "a higher grade" or "an elevated grade".
Of the nine participants, eight of these teachers taught 6th grade and one taught an advanced 7th grade course (Table 1).
By 15 Ma, a more advanced grade of ape also inhabited East African sites, overlapping with a few long-surviving lineages of STEM primates.
Its anti-tumour activity has shown to inhibit proliferation and migration of a number of advanced grade human tumors cell lines in a dose dependent manner [9 11].
In TCGA, BECN1 (but not BRCA1) expression was significantly lower in basal-like (P = 1.25E− 60) and HER2-enriched tumors (P = 6.85E− 16), tumors with TP53 mutations (P = 3.46E− 35), and tumors with an advanced histological grade (P = 5.39E− 05 for grade II, P = 5.01E− 20 for grade III) (Fig. 1C H).
In the clinic, JMJD6 associates with advanced grade, an aggressive phenotype, and serves as a marker of poor prognosis in breast cancer.
Similarly, in the METABRIC cohort, BECN1 (but not BRCA1) expression was also significantly lower in basal-like (P = 3.52E− 79) and HER2-enriched tumors (P = 3.51E− 40), tumors with TP53 mutations (P = 1.91E− 09), and tumors with an advanced histological grade (P = 2.79E− 07 for grade III) (Fig. 2C H).
Although they had preserved renal function and minimal proteinuria at the time of biopsy, half of the patients had an advanced pathological grade relative to their clinical manifestation.
Following the discovery of this advanced grade of ape at the 14-million-year-old site of Fort Ternan, Kenya (Leakey 1962), Louis Leakey's Kenyapithecus became a catchall for large-bodied Middle Miocene apes found throughout that country.
Grade is assessed by noting the most advanced grade present within cartilage, irrespective of its horizontal extent (grades 1 4: articular cartilage changes only; grades 5 6: cartilage and subchondral bone).
