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The NIF is an adjusted method for calculating the impact factor that takes into account the diversity of citing behavior in different disciplines and is inteded intended to assess the relative position of journals, potential employers, and researchers within each field [ 17].
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We implemented this concept ('symmetry of DNA curvature') in a suitably adjusted method (SymCurv), which permits us to attribute a symmetry of curvature score to each nucleotide on a given DNA sequence (see Methods for details).
The performance of an adjusted Chiang II method modified to include the Silcocks method of calculating variance for the final age interval was also compared with a Bayesian random effects model of life expectancy estimation.
The PRESS (prediction residual sum of squares) graphs shown use an adjusted regression method employed to prevent overfitting, as a 'leave one out method'.
An overview of the adjusted method is given in Figure 1.
The results are shown in Additional file 4. As already explained, it may be reasonable to choose a higher significance level than 0.05, and simulations were carried out for the adjusted method at a 0.10 significance level.
We used a Bayesian model and an adjusted likelihood method[ 13] to estimate values of true rates by facilities.
Applying the adjusted method based on Kendall's tau, we obtain a mid- p-value of 0.067, and the adjusted method based on Spearman's rho gives a mid- p-value of 0.063.
The sensitivities for each antigen for a fixed specificity of 90% are shown for the unadjusted and adjusted method in Table 3.
The IOP response of the trial eye was determined by the IOP change between baseline and 1 month in the trial eye alone (unadjusted method) and by adjusting for the IOP change in the fellow eye between the same visits (adjusted method).
The correlation of IOP change of both eyes between the same pre- and posttreatment visits was r = 0.81.The monocular trial (i.e., adjusted method) appears equivalent to testing each eye independently (i.e., unadjusted method); however, neither method is adequate to determine medication response to topical PGAs.
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