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Because several genes are lost in PWS, combined loss of Magel2 and other Prader-Willi candidate genes may have an additive deleterious effect.
Physician diagnosed OA of the back and pain at all sites were independent and stable correlates of QoL, and pain at multiple sites has an additive deleterious effect on QoL.
In conclusion, pain is the strongest musculoskeletal correlate of QoL, which has an additive deleterious effect on QoL, and mediates the effect of diagnosed OA (except in OA of the back).
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Experimental studies indicate that a combination of insults that induce modest oxidative stress can exert additive deleterious effects on motor neurons, suggesting that multiple exposures in real-world environments are important.
The combined effects of HIV and advancing age raise clinically relevant questions regarding the effective diagnosis and treatment of neurocognitive symptoms in HIV infection, especially with the likelihood of additive deleterious effects [ 23].
Researchers investigating distractions have unequivocally shown that multitasking and interrupting our thoughts has an enormous deleterious effect on our performance.
Occasionally, an excess of a specific element may have a deleterious effect on plant growth.
When used prescriptively, a style box has a deleterious effect.
When multiple traumas compound for an individual at a young age, it can have a deleterious effect.
Some investors expressed doubts that a diet fad could have such a deleterious effect on Krispy Kreme's results.
"Meltwater can have a really deleterious effect," said DeConto.
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