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In one group, patients received an additional single dose of GnRH agonist (0.5 mg leuprolide acetate) subcutaneously on day 6 after ICSI, whereas the patients in the other group did not.
Comparisons of OM prevalence between recipients of non-mixed PCV schedules showed very similar differences in prevalence between PCV groups, which supports a hypothesis that an additional single dose of an alternative PCV vaccine may have no detectable impact on clinical outcome.
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To assess the effect of an additional single mid-luteal dose of gonadotropin-releasing hormone agonist (GnRHa) on pregnancy and perinatal outcomes in hormonally substituted frozen embryo transfer (FET) cycles.
After review of safety and immunogenicity data from Part A, in Part B additional subjects were immunized with a single dose of 15 μg VLP vaccine (n = 2,537) or placebo (n = 1,011) and assessed for safety.
An additional five bleeds were treated with a single dose of rIX-FP, followed by the scheduled prophylaxis dose of rIX-FP within 30 h of the treatment dose.
The previous studies were carried out with different concentrations of the chemosensitizer drug followed by a single dose of TRAIL (Additional File 1).
Additional mechanistic studies indicated that a single dose of ethanol increased corticosterone levels (Collier et al. 2000) and also suppressed experimental induction of mRNA for a variety of cytokines (i.e., interferon alpha [IFN-α], interferon beta [IFN-β], IFN-γ, IL-6, IL-12, and IL-15) (Pruett et al. 2003).
IVF allows breeders to fertilize more than a hundred eggs with a single dose of semen.
Consequently, the increased and decreased inflammation associated with a high and low CCL3L1-containing segmental duplication, respectively, may explain why all subjects do not respond to a single dose of IVIG and require additional treatments.
Additional exploration of the potential utility of a single dose of Hib conjugate vaccine at 12 15 months of age as a complete routine immunization schedule is needed.
However, postoperative analgesic effect may end early with a single dose of caudal local anesthetic and additional analgesia may be required.
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