The MEPM RNA-seq data provide a transcriptional signature for this crosstalk, offering an additional readout to measure activation of these pathways.
Analysis of TFBSs close to the integration sites provides an additional readout to study the potential genotoxicity of vectors containing different promoters, enhancers and regulatory elements in a specific cell context.
Follow-up of these early meningiomas with a non-invasive imaging technique provides an additional readout in preclinical studies for chemoprevention of NF2-related tumors.
Thus, in this scenario neither MT nor LIP are sufficient for the formation of perceptual awareness, as at least an additional readout mechanism would be required, exhibiting integration properties compatible with the slow buildup of perceptual awareness.
This is reasonable because of the durations of the additional readout circuits (ranging from 20 to 410 ms) that cause UM to decay under T2.
As fragmentation precedes the degradation of dysfunctional mitochondria, we investigated an additional downstream readout and measured whether the observed increased mitochondrial fragmentation translates into changes of mitochondrial mass.
While XCI is a useful readout for pauciclonality, additional readouts, such as the number of tandem repeat sequences in the EBV genome [16] or the structure of the rearranged immunoglobulin heavy chain gene [17], might be useful in the future to confirm our estimates.
Furthermore, if the target is located in the very first row of the image, there would be an additional several tens of milliseconds of time advance in target detection given the redundant waiting time for pixel readout (Tread≈42 ms with a megapixel image sensor and a 25 MHz readout clock) before image processing in the traditional image readout-processing series structure in Figure 1a2.
Introduction of luciferase reporters into microbes provides an additional layer of information that is a readout of the association between organisms and how this might be affected by environmental conditions.
A rule-based model, parameterized through the measurement of several key readouts in the autophagy pathway, will be an additional focus of future efforts.
