Sentence examples for an additional mutation from inspiring English sources

In KRAS-mutated samples, 20% had an additional mutation in PIK3CA.

(4) The relatively high frequency of multiplets with two or more clustered mutations and an additional mutation at a distal location also argues for a chronocoordinate mutational event plus an independent single mutational event.

Therefore, we examined the effects of an additional mutation in the carbohydrate-binding site on the specificity of the lectin.

Most recently the BL21 DE3) strain commonly used for greater membrane protein expression15,25 was improved via an additional mutation in the T7 RNAP26.

This hypothesis would also suggest that the viability of a dam recB strain should be restored by an additional mutation (e.g., mutL or mutS) that inactivates mismatch repair.

Owing to the higher sensitivity, an additional mutation (T790M; including an ultra-low-level mutation, < 0.1%) was detected in the same reaction.

As a second step to improve vaccine safety, an additional mutation (W1266A) was engineered in the ganglioside binding pocket, resulting in reduced receptor binding, to produce M-BoNT/A1W M-BoNT/A1W

We tested the effect of an additional mutation in the UL41 gene on d106 immunogenicity and found that it did not improve the efficacy of the d106 vector, in contrast with results from other studies with UL41 gene mutants.

We show that the molecular and cellular deficits of an AS mouse model can be rescued by introducing an additional mutation at the inhibitory phosphorylation site of alphaCaMKII.

A genetic mutation usually leads to crippled and misfolded proteins, but in rare instances an additional mutation can bring a protein back to life.

Two sequences from China (AF502435 and AY249434) had an additional mutation at nucleotide position 119 from G → A which translated into an amino acid substitution from arginine to histidine.