The identification of stem-like cells within tumors has reshaped our understanding of cancer development, introducing an additional layer of complexity to the concept of intratumoral heterogeneity1.
"This Ceta saga has illustrated an additional layer of complexity that the UK will have to deal with," said Lourdes Catrain, a partner at law firm Hogan Lovells.
The discovery of the phosphorylation-dependent peptidyl-prolyl isomerase Pin1 added an additional layer of complexity to these regulatory networks.
While many Supreme Court cases require the interpretation of opaque statutory language, this case, Circuit City Stores v. Adams, No. 99-1379, han additionalnalayerer of complexity stemming from the law's reference to interstate commerce.
With a uterus transplant, there is an additional layer of complexity, because the pregnancy would be occurring within the transplanted organ, and no one knows how the transplant would adapt to pregnancy.
In the layoff case in particular, it's also important to provide employees with the likely emotional reactions of victims, because that will add an additional layer of complexity to their capacity to handle the dynamics of an actual situation.
Furthermore, with regard to CNS malignancies, a deeper understanding of how the immune system surveys the CNS adds an additional layer of complexity.
The presence of a retrograde gas-condensate fluid incorporates an additional layer of complexity to the performance of this class of reservoirs.
With a speaker implanted in the bell of the saxophone, the performer's playing of this modified instrument adds an additional layer of complexity that contributes significant instability and unpredictability in this re-embodied system.
The UN Refugee Agency states that competition over resources and jobs can generate animosity between forced migrants and host communities, adding an additional layer of complexity (UN Refugee Agency 2015, p. 6).
But obviously requiring that step would add an additional layer of complexity for users.
