Exact(2)
However, overexpression of constitutively active cdc42 (G12V) only very moderately activates Hog1, suggesting that an additional factor might be necessary for full activation of Ste20 (Raitt et al. 2000b).
An additional factor might be the heterology represented by a large allele length difference between microsatellite copies within a palindrome: would the mismatch represented by such heterology inhibit gene conversion, such that conversion events would be restricted to alleles of similar lengths?
Similar(58)
For a gene-gene interaction, the additional factor might be dichotomous, such as carrier versus non-carrier status, or additive, such as zero, one or two copies of the minor allele.
On the basis of our results and the literature, we now speculate that in such conditions, one additional factor might be that the MSC population is being gradually exhausted in vivo because of loss of ECM interactions and subsequent cell death.
From our data, we conclude that Bcl11b regulates progenitor proliferation as well as differentiation in a non-cell autonomous fashion but that different additional factors might be involved in the regulation of these processes.
But in Ibn Khaldūn's case two additional factors might be suspected a certain restlessness and a capacity to make enemies, which may account for his constant complaints about the "intriguers" who turned his employers against him.
Like the financial allocation formula used by the Ministry of Health [ 34], which combines the levels of population with other indicators of need, additional factors might be built into the allocation formula for a more sensible and fairer distribution of the health workforce.
However, additional factors might be responsible for the inadequate practice of patient education seen in our sample.
Such additional factors might be any of the nuclear transcription factors involved in mitochondrial function or any of the mitochondrial transcription or replication factors.
Some additional factors might be required that could be provided by niche.
Additional factors might be interacting with 15S rRNA and thus ameliorating the SMDC effect.
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